Abuse of substances to change body image is highly dangerous. There are a large number of side effects that come with using drugs, which vary with the substance. Side effects include heart problems, a danger of stroke, irregular pulse, depression, and even death. Another risk is the chance that a body is overwhelmed or cannot react appropriately to a new substance, which may cause a heart attack or sudden death.

Alternatives to taking substances include maintaining a healthy diet, like cutting down on fatty foods and eating in moderation; exercising regularly and working out; reducing or abstaining from potentially dangerous materials such as tobacco and alcohol.